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Linking Epigenetics, Metabolism and Cancer: Lessons From SIRT6

In recent years, chromatin regulators have emerged as key modulators in cancer. We discovered that the mammalian histone deacetylase SIRT6 is a key chromatin factor, modulating expression of metabolic, developmental, and ribosomal protein genes. In recent studies, we identified a loss of function mu...

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Bibliografiska uppgifter
I publikationen:Innov Aging
Huvudupphovsman: Mostoslavsky, Raul
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7741545/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igaa057.2651
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