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Chromatin and beyond: the multitasking roles for SIRT6

In recent years there has been a large expansion in our understanding of SIRT6 biology, including its structure, regulation, biochemical activity and biological roles. SIRT6 functions as an ADP-ribosylase and NAD(+)-dependent deacylase of both acetyl groups and long-chain fatty acyl groups. Through...

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Detalhes bibliográficos
Main Authors: Kugel, Sita, Mostoslavsky, Raul
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3912268/
https://ncbi.nlm.nih.gov/pubmed/24438746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2013.12.002
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