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Linking Epigenetics, Metabolism and Cancer: Lessons From SIRT6
In recent years, chromatin regulators have emerged as key modulators in cancer. We discovered that the mammalian histone deacetylase SIRT6 is a key chromatin factor, modulating expression of metabolic, developmental, and ribosomal protein genes. In recent studies, we identified a loss of function mu...
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| Veröffentlicht in: | Innov Aging |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7741545/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igaa057.2651 |
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