Long Life Family Study Shows Reduced Coronary Artery Disease Despite High Polygenic Hazard Scores

Polygenic hazard scores (PHS) for coronary artery disease (CAD) quantify individuals with age-specific genetic risk for CAD. We evaluated how well the PHS predict age at onset of CAD in the Long Life Family Study (LLFS; families selected for exceptional longevity), compared to the Family Heart Study...

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Pubblicato in:Innov Aging
Autori principali: Feitosa, Mary, Kuipers, Allison, Wojczynski, Mary, Wang, Lihua, Perls, Thomas, Christensen, Kaare, Zmuda, Joseph, Province, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7741003/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igaa057.685
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