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Generation of Human Neurons and Oligodendrocytes from Pluripotent Stem Cells for Modeling Neuron-oligodendrocyte Interactions

In Alzheimer’s disease (AD) and other neurodegenerative disorders, oligodendroglial failure is a common early pathological feature, but how it contributes to disease development and progression, particularly in the gray matter of the brain, remains largely unknown. The dysfunction of oligodendrocyte...

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Détails bibliographiques
Publié dans:J Vis Exp
Auteurs principaux: Assetta, Benedetta, Tang, Changyong, Bian, Jing, O’Rourke, Ryan, Connolly, Kevin, Brickler, Thomas, Chetty, Sundari, Huang, Yu-Wen Alvin
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7739515/
https://ncbi.nlm.nih.gov/pubmed/33226027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/61778
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