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Generation of serotonin neurons from human pluripotent stem cells

Serotonin neurons located in the raphe nucleus of the hindbrain have crucial roles in regulating brain functions and have been implicated in various psychiatric disorders. Yet functional human serotonin neurons are not available for in vitro studies. Through manipulation of the WNT pathway, we demon...

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書目詳細資料
發表在:Nat Biotechnol
Main Authors: Lu, Jianfeng, Zhong, Xuefei, Liu, Huisheng, Hao, Ling, Huang, Cindy Tzu-Ling, Sherafat, Mohammad Amin, Jones, Jeffrey, Ayala, Melvin, Li, Lingjun, Zhang, Su-Chun
格式: Artigo
語言:Inglês
出版: 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4711820/
https://ncbi.nlm.nih.gov/pubmed/26655496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3435
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