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Generation of neuropeptidergic hypothalamic neurons from human pluripotent stem cells

Hypothalamic neurons orchestrate many essential physiological and behavioral processes via secreted neuropeptides, and are relevant to human diseases such as obesity, narcolepsy and infertility. We report the differentiation of human pluripotent stem cells into many of the major types of neuropeptid...

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Dettagli Bibliografici
Pubblicato in:Development
Autori principali: Merkle, Florian T., Maroof, Asif, Wataya, Takafumi, Sasai, Yoshiki, Studer, Lorenz, Eggan, Kevin, Schier, Alexander F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists 2015
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325380/
https://ncbi.nlm.nih.gov/pubmed/25670790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.117978
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