Generation of neuropeptidergic hypothalamic neurons from human pluripotent stem cells

Hypothalamic neurons orchestrate many essential physiological and behavioral processes via secreted neuropeptides, and are relevant to human diseases such as obesity, narcolepsy and infertility. We report the differentiation of human pluripotent stem cells into many of the major types of neuropeptid...

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Bibliografiske detaljer
Udgivet i:Development
Main Authors: Merkle, Florian T., Maroof, Asif, Wataya, Takafumi, Sasai, Yoshiki, Studer, Lorenz, Eggan, Kevin, Schier, Alexander F.
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists 2015
Fag:
Stem Cells and Regeneration
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325380/
https://ncbi.nlm.nih.gov/pubmed/25670790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.117978
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