Generation of a Motor Nerve Organoid with Human Stem Cell-Derived Neurons

During development, axons spontaneously assemble into a fascicle to form nerves and tracts in the nervous system as they extend within a spatially constrained path. However, understanding of the axonal fascicle has been hampered by lack of an in vitro model system. Here, we report generation of a ne...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Kawada, Jiro, Kaneda, Shohei, Kirihara, Takaaki, Maroof, Asif, Levi, Timothée, Eggan, Kevin, Fujii, Teruo, Ikeuchi, Yoshiho
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5831012/
https://ncbi.nlm.nih.gov/pubmed/29107592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.09.021
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