Efficient Generation of Myelinating Oligodendrocytes from Primary Progressive Multiple Sclerosis Patients by Induced Pluripotent Stem Cells

Multiple sclerosis (MS) is a chronic demyelinating disease of unknown etiology that affects the CNS. While current therapies are primarily directed against the immune system, the new challenge is to address progressive MS with remyelinating and neuroprotective strategies. Here, we develop a highly r...

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Main Authors: Douvaras, Panagiotis, Wang, Jing, Zimmer, Matthew, Hanchuk, Stephanie, O’Bara, Melanie A., Sadiq, Saud, Sim, Fraser J., Goldman, James, Fossati, Valentina
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176529/
https://ncbi.nlm.nih.gov/pubmed/25254339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.06.012
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