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Induction of Myelinating Oligodendrocytes in Human Cortical Spheroids

Organoid technologies provide an accessible system to examine cellular composition, interactions, and organization in the developing human brain, but previously have lacked oligodendrocytes, the myelinating glia of the central nervous system. Here we reproducibly generate oligodendrocytes and myelin...

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Dades bibliogràfiques
Publicat a:Nat Methods
Autors principals: Madhavan, Mayur, Nevin, Zachary S., Shick, H. Elizabeth, Garrison, Eric, Clarkson-Paredes, Cheryl, Karl, Molly, Clayton, Benjamin L.L., Factor, Daniel C., Allan, Kevin C., Barbar, Lilianne, Jain, Tanya, Douvaras, Panagiotis, Fossati, Valentina, Miller, Robert H., Tesar, Paul J.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6508550/
https://ncbi.nlm.nih.gov/pubmed/30046099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-018-0081-4
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