Induction of Myelinating Oligodendrocytes in Human Cortical Spheroids

Organoid technologies provide an accessible system to examine cellular composition, interactions, and organization in the developing human brain, but previously have lacked oligodendrocytes, the myelinating glia of the central nervous system. Here we reproducibly generate oligodendrocytes and myelin...

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Publicado no:Nat Methods
Main Authors: Madhavan, Mayur, Nevin, Zachary S., Shick, H. Elizabeth, Garrison, Eric, Clarkson-Paredes, Cheryl, Karl, Molly, Clayton, Benjamin L.L., Factor, Daniel C., Allan, Kevin C., Barbar, Lilianne, Jain, Tanya, Douvaras, Panagiotis, Fossati, Valentina, Miller, Robert H., Tesar, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6508550/
https://ncbi.nlm.nih.gov/pubmed/30046099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-018-0081-4
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