Epigenetic Modulation of Human Induced Pluripotent Stem Cell Differentiation to Oligodendrocytes

Pluripotent stem cells provide an invaluable tool for generating human, disease-relevant cells. Multiple sclerosis is an inflammatory demyelinating disease of the central nervous system, characterized by myelin damage. Oligodendrocytes are the myelinating cells of the central nervous system (CNS); t...

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Main Authors: Panagiotis Douvaras, Tomasz Rusielewicz, Kwi Hye Kim, Jeffery D. Haines, Patrizia Casaccia, Valentina Fossati
Format: Artigo
Jezik:Inglês
Izdano: MDPI AG 2016-04-01
Serija:International Journal of Molecular Sciences
Teme:
human induced pluripotent stem cells
oligodendrocyte differentiation
histone modifications
Online dostop:http://www.mdpi.com/1422-0067/17/4/614
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