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Epigenetic memory loss in aging oligodendrocytes in the corpus callosum

In this study we address the hypothesis that aging modifies the intrinsic properties of oligodendrocytes, the myelin-forming cells of the brain. According to our model, an “epigenetic memory” is stored in the chromatin of the oligodendrocyte lineage cells and is responsible for the maintenance of a...

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Detalles Bibliográficos
Autores principales: Siming, Shen, Aixiao, Liu, Jiadong, Li, Candy, Wolubah, Patrizia, Casaccia-Bonnefil
Formato: Artigo
Lenguaje:Inglês
Publicado: 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323437/
https://ncbi.nlm.nih.gov/pubmed/17182153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2006.10.026
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