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Metabolic remodelling of glucose, fatty acid and redox pathways in the heart of type 2 diabetic mice

Type-2 diabetes (T2DM) leads to reduced myocardial performance, and eventually heart failure. Excessive accumulation of lipids and glucose is central to T2DM cardiomyopathy. Previous data showed that palmitate (Palm) or glutathione preserved heart mitochondrial energy/redox balance under excess gluc...

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Bibliografiska uppgifter
I publikationen:J Physiol
Huvudupphovsmän: Cortassa, Sonia, Caceres, Viviane, Tocchetti, Carlo G., Bernier, Michel, de Cabo, Rafael, Paolocci, Nazareno, Sollott, Steven J., Aon, Miguel A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7739175/
https://ncbi.nlm.nih.gov/pubmed/30462352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP276824
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