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The AbDesign computational pipeline for modular backbone assembly and design of binders and enzymes

The functional sites of many protein families are dominated by diverse backbone regions that lack secondary structure (loops) but fold stably into their functionally competent state. Nevertheless, the design of structured loop regions from scratch, especially in functional sites, has met with great...

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Bibliographische Detailangaben
Veröffentlicht in:Protein Sci
Hauptverfasser: Lipsh‐Sokolik, Rosalie, Listov, Dina, Fleishman, Sarel J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley & Sons, Inc. 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7737780/
https://ncbi.nlm.nih.gov/pubmed/33040418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3970
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