Pharmacological inhibition of syntenin PDZ2 domain impairs breast cancer cell activities and exosome loading with syndecan and EpCAM cargo

Exosomes support cell‐to‐cell communication in physiology and disease, including cancer. We currently lack tools, such as small chemicals, capable of modifying exosome composition and activity in a specific manner. Building on our previous understanding of how syntenin, and its PDZ partner syndecan...

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Publicado en:J Extracell Vesicles
Autores principales: Leblanc, R., Kashyap, R., Barral, K., Egea‐Jimenez, A.L., Kovalskyy, D., Feracci, M., Garcia, M., Derviaux, C., Betzi, S., Ghossoub, R., Platonov, M., Roche, P., Morelli, X., Hoffer, L., Zimmermann, Pascale
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2020
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Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7737769/
https://ncbi.nlm.nih.gov/pubmed/33343836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jev2.12039
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