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Pharmacological inhibition of syntenin PDZ2 domain impairs breast cancer cell activities and exosome loading with syndecan and EpCAM cargo

Exosomes support cell‐to‐cell communication in physiology and disease, including cancer. We currently lack tools, such as small chemicals, capable of modifying exosome composition and activity in a specific manner. Building on our previous understanding of how syntenin, and its PDZ partner syndecan...

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Bibliografski detalji
Izdano u:J Extracell Vesicles
Glavni autori: Leblanc, R., Kashyap, R., Barral, K., Egea‐Jimenez, A.L., Kovalskyy, D., Feracci, M., Garcia, M., Derviaux, C., Betzi, S., Ghossoub, R., Platonov, M., Roche, P., Morelli, X., Hoffer, L., Zimmermann, Pascale
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7737769/
https://ncbi.nlm.nih.gov/pubmed/33343836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jev2.12039
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