Pharmacological inhibition of syntenin PDZ2 domain impairs breast cancer cell activities and exosome loading with syndecan and EpCAM cargo

Exosomes support cell‐to‐cell communication in physiology and disease, including cancer. We currently lack tools, such as small chemicals, capable of modifying exosome composition and activity in a specific manner. Building on our previous understanding of how syntenin, and its PDZ partner syndecan...

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Detalhes bibliográficos
Publicado no:J Extracell Vesicles
Main Authors: Leblanc, R., Kashyap, R., Barral, K., Egea‐Jimenez, A.L., Kovalskyy, D., Feracci, M., Garcia, M., Derviaux, C., Betzi, S., Ghossoub, R., Platonov, M., Roche, P., Morelli, X., Hoffer, L., Zimmermann, Pascale
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7737769/
https://ncbi.nlm.nih.gov/pubmed/33343836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jev2.12039
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