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Suppression of glycogen synthesis as a treatment for Lafora disease: Establishing the window of opportunity.
Lafora disease (LD) is a fatal adolescence-onset neurodegenerative condition. The hallmark of LD is the accumulation of aberrant glycogen aggregates called Lafora bodies (LBs) in the brain and other tissues. Impeding glycogen synthesis from early embryonic stages by genetic suppression of glycogen s...
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| Publicado no: | Neurobiol Dis |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7736642/ https://ncbi.nlm.nih.gov/pubmed/33171226 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2020.105173 |
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