Neurodegeneration and functional impairments associated with glycogen synthase accumulation in a mouse model of Lafora disease

Lafora disease (LD) is caused by mutations in either the laforin or malin gene. The hallmark of the disease is the accumulation of polyglucosan inclusions called Lafora Bodies (LBs). Malin knockout (KO) mice present polyglucosan accumulations in several brain areas, as do patients of LD. These struc...

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Главные авторы: Valles-Ortega, Jordi, Duran, Jordi, Garcia-Rocha, Mar, Bosch, Carles, Saez, Isabel, Pujadas, Lluís, Serafin, Anna, Cañas, Xavier, Soriano, Eduardo, Delgado-García, José M, Gruart, Agnès, Guinovart, Joan J
Формат: Artigo
Язык:Inglês
Опубликовано: WILEY-VCH Verlag 2011
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3377110/
https://ncbi.nlm.nih.gov/pubmed/21882344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201100174
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