Brain necrosis in adult patients after proton therapy: Is there evidence for dependency on linear energy transfer (LET)?

PURPOSE: To investigate if radiographic imaging changes defined as necrosis correlate with regions in the brain with elevated linear energy transfer (LET) for proton radiation therapy treatments with partial brain involvement in central nervous system (CNS) and head and neck (H&N) cancer patient...

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Bibliografiska uppgifter
I publikationen:Int J Radiat Oncol Biol Phys
Huvudupphovsmän: Niemierko, Andrzej, Schuemann, Jan, Niyazi, Maximilian, Giantsoudi, Drosoula, Maquilan, Genevieve, Shih, Helen A, Paganetti, Harald
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2020
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7736370/
https://ncbi.nlm.nih.gov/pubmed/32911019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2020.08.058
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