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Linear energy transfer (LET)-Guided Optimization in intensity modulated proton therapy (IMPT): feasibility study and clinical potential

PURPOSE: To investigate the feasibility and potential clinical benefit of linear energy transfer (LET) guided plan optimization in intensity-modulated proton therapy (IMPT). METHODS AND MATERIALS: A multi-criteria optimization (MCO) module was utilized to generate series of Pareto-optimal IMPT base...

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Detalhes bibliográficos
Publicado no:Int J Radiat Oncol Biol Phys
Main Authors: Giantsoudi, Drosoula, Grassberger, Clemens, Craft, David, Niemierko, Andrzej, Trofimov, Alexei, Paganetti, Harald
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520412/
https://ncbi.nlm.nih.gov/pubmed/23790771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2013.05.013
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