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Brain necrosis in adult patients after proton therapy: Is there evidence for dependency on linear energy transfer (LET)?

PURPOSE: To investigate if radiographic imaging changes defined as necrosis correlate with regions in the brain with elevated linear energy transfer (LET) for proton radiation therapy treatments with partial brain involvement in central nervous system (CNS) and head and neck (H&N) cancer patient...

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Detalhes bibliográficos
Publicado no:Int J Radiat Oncol Biol Phys
Main Authors: Niemierko, Andrzej, Schuemann, Jan, Niyazi, Maximilian, Giantsoudi, Drosoula, Maquilan, Genevieve, Shih, Helen A, Paganetti, Harald
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7736370/
https://ncbi.nlm.nih.gov/pubmed/32911019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2020.08.058
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