MeCP2 links heterochromatin condensates and neurodevelopmental disease

MeCP2 (methyl CpG binding protein 2) is a key component of constitutive heterochromatin, which plays important roles in chromosome maintenance and transcriptional silencing(1-3). Mutations in MeCP2 cause Rett syndrome (RTT)(3-5), a postnatal progressive neurodevelopmental disorder associated with se...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Nature
Autors principals: Li, Charles H., Coffey, Eliot L., Dall’Agnese, Alessandra, Hannett, Nancy M., Tang, Xin, Henninger, Jonathan E., Platt, Jesse M., Oksuz, Ozgur, Zamudio, Alicia V., Afeyan, Lena K., Schuijers, Jurian, Liu, X. Shawn, Markoulaki, Styliani, Lungjangwa, Tenzin, LeRoy, Gary, Svoboda, Devon S., Wogram, Emile, Lee, Tong Ihn, Jaenisch, Rudolf, Young, Richard A.
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7735819/
https://ncbi.nlm.nih.gov/pubmed/32698189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-2574-4
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars