Mediator condensates localize signaling factors to key cell identity genes

The gene expression programs that define each cell’s identity are controlled by master transcription factors (TFs) that bind cell-type specific enhancers, as well as signaling factors, which bring extracellular stimuli to these enhancers. Recent studies have revealed that master TFs form phase-separ...

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Detaylı Bibliyografya
Yayımlandı:Mol Cell
Asıl Yazarlar: Zamudio, Alicia V., Dall’Agnese, Alessandra, Henninger, Jonathan E., Manteiga, John C., Afeyan, Lena K., Hannett, Nancy M., Coffey, Eliot L., Li, Charles H., Oksuz, Ozgur, Sabari, Benjamin R., Boija, Ann, Klein, Isaac A., Hawken, Susana W., Spille, Jan-Hendrik, Decker, Tim-Michael, Cisse, Ibrahim I., Abraham, Brian J., Lee, Tong I., Taatjes, Dylan J., Schuijers, Jurian, Young, Richard A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6898777/
https://ncbi.nlm.nih.gov/pubmed/31563432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.08.016
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