Mediator condensates localize signaling factors to key cell identity genes

The gene expression programs that define each cell’s identity are controlled by master transcription factors (TFs) that bind cell-type specific enhancers, as well as signaling factors, which bring extracellular stimuli to these enhancers. Recent studies have revealed that master TFs form phase-separ...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Cell
Prif Awduron: Zamudio, Alicia V., Dall’Agnese, Alessandra, Henninger, Jonathan E., Manteiga, John C., Afeyan, Lena K., Hannett, Nancy M., Coffey, Eliot L., Li, Charles H., Oksuz, Ozgur, Sabari, Benjamin R., Boija, Ann, Klein, Isaac A., Hawken, Susana W., Spille, Jan-Hendrik, Decker, Tim-Michael, Cisse, Ibrahim I., Abraham, Brian J., Lee, Tong I., Taatjes, Dylan J., Schuijers, Jurian, Young, Richard A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6898777/
https://ncbi.nlm.nih.gov/pubmed/31563432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.08.016
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