Nucleolar Stress Induction by Oxaliplatin and Derivatives

Platinum(II) compounds are a critical class of chemotherapeutic agents. Recent studies have highlighted the ability of a subset of Pt(II) compounds, including oxaliplatin but not cisplatin, to induce cytotoxicity via nucleolar stress rather than a canonical DNA damage response. In this study, influe...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Sutton, Emily C., McDevitt, Christine E., Prochnau, Jack Y., Yglesias, Matthew V., Mroz, Austin M., Yang, Min Chieh, Cunningham, Rachael M., Hendon, Christopher H., DeRose, Victoria J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7735645/
https://ncbi.nlm.nih.gov/pubmed/31670961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b10319
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