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Monofunctional Platinum(II) Compounds and Nucleolar Stress: Is Phenanthriplatin Unique?

Platinum anticancer therapeutics are widely used in a variety of chemotherapy regimens. Recent work has revealed that the cytotoxicity of oxaliplatin and phenanthriplatin is through induction of ribosome biogenesis stress pathways, differentiating them from cisplatin and other compounds that mainly...

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Bibliografische gegevens
Gepubliceerd in:J Biol Inorg Chem
Hoofdauteurs: McDevitt, Christine E., Yglesias, Matthew V., Mroz, Austin M., Sutton, Emily C., Yang, Min Chieh, Hendon, Christopher H., DeRose, Victoria J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7660985/
https://ncbi.nlm.nih.gov/pubmed/31494760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-019-01707-9
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