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Monofunctional Platinum(II) Compounds and Nucleolar Stress: Is Phenanthriplatin Unique?

Platinum anticancer therapeutics are widely used in a variety of chemotherapy regimens. Recent work has revealed that the cytotoxicity of oxaliplatin and phenanthriplatin is through induction of ribosome biogenesis stress pathways, differentiating them from cisplatin and other compounds that mainly...

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Detalhes bibliográficos
Publicado no:J Biol Inorg Chem
Main Authors: McDevitt, Christine E., Yglesias, Matthew V., Mroz, Austin M., Sutton, Emily C., Yang, Min Chieh, Hendon, Christopher H., DeRose, Victoria J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7660985/
https://ncbi.nlm.nih.gov/pubmed/31494760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-019-01707-9
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