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Pt-induced crosslinks promote target enrichment and protection from serum nucleases

Identifying the interactions of small molecules with biomolecules in complex cellular environments is a significant challenge. As one important example, despite being widely used for decades, much is still not understood regarding the cellular targets of Pt(II)-based anticancer drugs. In this study...

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Detalles Bibliográficos
Publicado en:J Inorg Biochem
Main Authors: Cunningham, Rachael M., Hickey, Anna M., Wilson, Jesse W., Plakos, Kory J. I., DeRose, Victoria J.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7703794/
https://ncbi.nlm.nih.gov/pubmed/30245274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinorgbio.2018.09.007
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