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Pan-Sigma Receptor Modulator RC-106 Induces Terminal Unfolded Protein Response In In Vitro Pancreatic Cancer Model

Pancreatic cancer (PC) remains one of the most lethal cancers worldwide. Sigma receptors (SRs) have been proposed as cancer therapeutic targets. Their main localization suggests they play a potential role in ER stress and in the triggering of the unfolded protein response (UPR). Here, we investigate...

詳細記述

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書誌詳細
出版年:Int J Mol Sci
主要な著者: Cortesi, Michela, Zamagni, Alice, Pignatta, Sara, Zanoni, Michele, Arienti, Chiara, Rossi, Daniela, Collina, Simona, Tesei, Anna
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7734580/
https://ncbi.nlm.nih.gov/pubmed/33260926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21239012
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