Sigma Receptors as Endoplasmic Reticulum Stress “Gatekeepers” and their Modulators as Emerging New Weapons in the Fight Against Cancer

Despite the interest aroused by sigma receptors (SRs) in the area of oncology, their role in tumor biology remains enigmatic. The predominant subcellular localization and main site of activity of SRs are the endoplasmic reticulum (ER). Current literature data, including recent findings on the sigma...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Front Pharmacol
Auteurs principaux: Tesei, Anna, Cortesi, Michela, Zamagni, Alice, Arienti, Chiara, Pignatta, Sara, Zanoni, Michele, Paolillo, Mayra, Curti, Daniela, Rui, Marta, Rossi, Daniela, Collina, Simona
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2018
Sujets:
Pharmacology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6048940/
https://ncbi.nlm.nih.gov/pubmed/30042674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00711
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