Sigma Receptors as Endoplasmic Reticulum Stress “Gatekeepers” and their Modulators as Emerging New Weapons in the Fight Against Cancer

Despite the interest aroused by sigma receptors (SRs) in the area of oncology, their role in tumor biology remains enigmatic. The predominant subcellular localization and main site of activity of SRs are the endoplasmic reticulum (ER). Current literature data, including recent findings on the sigma...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Tesei, Anna, Cortesi, Michela, Zamagni, Alice, Arienti, Chiara, Pignatta, Sara, Zanoni, Michele, Paolillo, Mayra, Curti, Daniela, Rui, Marta, Rossi, Daniela, Collina, Simona
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6048940/
https://ncbi.nlm.nih.gov/pubmed/30042674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00711
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