Sigma Receptors as Endoplasmic Reticulum Stress “Gatekeepers” and their Modulators as Emerging New Weapons in the Fight Against Cancer

Despite the interest aroused by sigma receptors (SRs) in the area of oncology, their role in tumor biology remains enigmatic. The predominant subcellular localization and main site of activity of SRs are the endoplasmic reticulum (ER). Current literature data, including recent findings on the sigma...

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Bibliographische Detailangaben
Veröffentlicht in:Front Pharmacol
Hauptverfasser: Tesei, Anna, Cortesi, Michela, Zamagni, Alice, Arienti, Chiara, Pignatta, Sara, Zanoni, Michele, Paolillo, Mayra, Curti, Daniela, Rui, Marta, Rossi, Daniela, Collina, Simona
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Pharmacology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6048940/
https://ncbi.nlm.nih.gov/pubmed/30042674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00711
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