Development of Fc-fused Cocaine Hydrolase for Cocaine Addiction Treatment: Catalytic and Pharmacokinetic Properties

Cocaine abuse is a world-wide public health and social problem without a U.S. Food and Drug Administration (FDA)-approved medication. Accelerating cocaine metabolism that produces biologically inactive metabolites by administration of an efficient cocaine hydrolase (CocH) has been recognized as a pr...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:AAPS J
Hauptverfasser: Chen, Xiabin, Deng, Jing, Cui, Wenpeng, Hou, Shurong, Zhang, Jinling, Zheng, Xirong, Ding, Xin, Wei, Huimei, Zhou, Ziyuan, Kim, Kyungbo, Zhan, Chang-Guo, Zheng, Fang
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7734446/
https://ncbi.nlm.nih.gov/pubmed/29556863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-018-0214-9
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge