Expansion of a Specific Plasmodium falciparum PfMDR1 Haplotype in Southeast Asia with Increased Substrate Transport

Artemisinin-based combination therapies (ACTs) have been vital in reducing malaria mortality rates since the 2000s. Their efficacy, however, is threatened by the emergence and spread of artemisinin resistance in Southeast Asia. The Plasmodium falciparum multidrug resistance protein 1 (PfMDR1) transp...

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Publicat a:mBio
Autors principals: Calçada, Carla, Silva, Miguel, Baptista, Vitória, Thathy, Vandana, Silva-Pedrosa, Rita, Granja, Diana, Ferreira, Pedro Eduardo, Gil, José Pedro, Fidock, David A., Veiga, Maria Isabel
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7733942/
https://ncbi.nlm.nih.gov/pubmed/33262257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02093-20
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