PfMDR1: Mechanisms of Transport Modulation by Functional Polymorphisms

ATP-Binding Cassette (ABC) transporters are efflux pumps frequently associated with multidrug resistance in many biological systems, including malaria. Antimalarial drug-resistance involves an ABC transporter, PfMDR1, a homologue of P-glycoprotein in humans. Twenty years of research have shown that...

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Dettagli Bibliografici
Autori principali: Ferreira, Pedro Eduardo, Holmgren, Gabrielle, Veiga, Maria Isabel, Uhlén, Per, Kaneko, Akira, Gil, José Pedro
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164660/
https://ncbi.nlm.nih.gov/pubmed/21912647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023875
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