Expansion of a Specific Plasmodium falciparum PfMDR1 Haplotype in Southeast Asia with Increased Substrate Transport

Artemisinin-based combination therapies (ACTs) have been vital in reducing malaria mortality rates since the 2000s. Their efficacy, however, is threatened by the emergence and spread of artemisinin resistance in Southeast Asia. The Plasmodium falciparum multidrug resistance protein 1 (PfMDR1) transp...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Calçada, Carla, Silva, Miguel, Baptista, Vitória, Thathy, Vandana, Silva-Pedrosa, Rita, Granja, Diana, Ferreira, Pedro Eduardo, Gil, José Pedro, Fidock, David A., Veiga, Maria Isabel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7733942/
https://ncbi.nlm.nih.gov/pubmed/33262257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02093-20
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