Expansion of a Specific Plasmodium falciparum PfMDR1 Haplotype in Southeast Asia with Increased Substrate Transport

Artemisinin-based combination therapies (ACTs) have been vital in reducing malaria mortality rates since the 2000s. Their efficacy, however, is threatened by the emergence and spread of artemisinin resistance in Southeast Asia. The Plasmodium falciparum multidrug resistance protein 1 (PfMDR1) transp...

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Bibliografische gegevens
Gepubliceerd in:mBio
Hoofdauteurs: Calçada, Carla, Silva, Miguel, Baptista, Vitória, Thathy, Vandana, Silva-Pedrosa, Rita, Granja, Diana, Ferreira, Pedro Eduardo, Gil, José Pedro, Fidock, David A., Veiga, Maria Isabel
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2020
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7733942/
https://ncbi.nlm.nih.gov/pubmed/33262257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02093-20
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