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Retinol binding protein 4 primes the NLRP3 inflammasome by signaling through Toll-like receptors 2 and 4

Adipose tissue (AT) inflammation contributes to systemic insulin resistance. In obesity and type 2 diabetes (T2D), retinol binding protein 4 (RBP4), the major retinol carrier in serum, is elevated in AT and has proinflammatory effects which are mediated partially through Toll-like receptor 4 (TLR4)....

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Proc Natl Acad Sci U S A
मुख्य लेखकों: Moraes-Vieira, Pedro M., Yore, Mark M., Sontheimer-Phelps, Alexandra, Castoldi, Angela, Norseen, Julie, Aryal, Pratik, Simonyté Sjödin, Kotryna, Kahn, Barbara B.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2020
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7733787/
https://ncbi.nlm.nih.gov/pubmed/33214151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2013877117
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