Triclosan leads to dysregulation of the metabolic regulator FGF21 exacerbating high fat diet-induced nonalcoholic fatty liver disease

Triclosan (TCS), employed as an antiseptic and disinfectant, comes into direct contact with humans through a plethora of consumer products and its rising environmental release. We have demonstrated that TCS promotes liver tumorigenesis in mice, yet the biological and molecular mechanisms by which TC...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Yueh, Mei-Fei, He, Feng, Chen, Chen, Vu, Catherine, Tripathi, Anupriya, Knight, Rob, Karin, Michael, Chen, Shujuan, Tukey, Robert H.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7733785/
https://ncbi.nlm.nih.gov/pubmed/33229553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2017129117
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