Impaired mitochondrial fat oxidation induces FGF21 in muscle

Fatty acids are the primary fuel source for skeletal muscle during most of our daily activities and impaired fatty acid oxidation (FAO) is associated with insulin resistance. We have developed a mouse model of impaired FAO by deleting carnitine palmitoyltransferase-1b specifically in skeletal muscle...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Vandanmagsar, Bolormaa, Warfel, Jaycob D., Wicks, Shawna E., Ghosh, Sujoy, Salbaum, J. Michael, Burk, David, Dubuisson, Olga S., Mendoza, Tamra M., Zhang, Jingying, Noland, Robert C., Mynatt, Randall L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4880522/
https://ncbi.nlm.nih.gov/pubmed/27184848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.04.057
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