Impaired mitochondrial fat oxidation induces FGF21 in muscle

Fatty acids are the primary fuel source for skeletal muscle during most of our daily activities and impaired fatty acid oxidation (FAO) is associated with insulin resistance. We have developed a mouse model of impaired FAO by deleting carnitine palmitoyltransferase-1b specifically in skeletal muscle...

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Gepubliceerd in:Cell Rep
Hoofdauteurs: Vandanmagsar, Bolormaa, Warfel, Jaycob D., Wicks, Shawna E., Ghosh, Sujoy, Salbaum, J. Michael, Burk, David, Dubuisson, Olga S., Mendoza, Tamra M., Zhang, Jingying, Noland, Robert C., Mynatt, Randall L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4880522/
https://ncbi.nlm.nih.gov/pubmed/27184848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.04.057
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