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A low fat diet ameliorates pathology but retains beneficial effects associated with CPT1b knockout in skeletal muscle

Inhibiting fatty acid oxidation is one approach to lowering glucose levels in diabetes. Skeletal muscle specific Carnitine Palmitoyltransferase 1b knockout mice (Cpt1b(m-/-)) comprise a model of impaired fat oxidation; and have decreased fat mass and enhanced glucose disposal and muscle oxidative ca...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Warfel, Jaycob D., Vandanmagsar, Bolormaa, Wicks, Shawna E., Zhang, Jingying, Noland, Robert C., Mynatt, Randall L.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5730174/
https://ncbi.nlm.nih.gov/pubmed/29240830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0188850
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