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Extensive metabolic remodeling after limiting mitochondrial lipid burden is consistent with an improved metabolic health profile

Mitochondrial lipid overload in skeletal muscle contributes to insulin resistance, and strategies limiting this lipid pressure improve glucose homeostasis; however, comprehensive cellular adaptations that occur in response to such an intervention have not been reported. Herein, mice with skeletal mu...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Ghosh, Sujoy, Wicks, Shawna E., Vandanmagsar, Bolormaa, Mendoza, Tamra M., Bayless, David S., Salbaum, J. Michael, Dearth, Stephen P., Campagna, Shawn R., Mynatt, Randall L., Noland, Robert C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6699851/
https://ncbi.nlm.nih.gov/pubmed/31097541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006074
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