Intravenous injection of the oncolytic virus M1 awakens antitumor T cells and overcomes resistance to checkpoint blockade

Reversing the highly immunosuppressive tumor microenvironment (TME) is essential to achieve long-term efficacy with cancer immunotherapy. Despite the impressive clinical response to checkpoint blockade in multiple types of cancer, only a minority of patients benefit from this approach. Here, we repo...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Liu, Yang, Cai, Jing, Liu, Wenfeng, Lin, Yuan, Guo, Li, Liu, Xincheng, Qin, Zhen, Xu, Cuiying, Zhang, Yanming, Su, Xingwen, Deng, Kai, Yan, Guangmei, Liang, Jiankai
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7733593/
https://ncbi.nlm.nih.gov/pubmed/33311488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-03285-0
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