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Overcoming Barriers in Oncolytic Virotherapy with HDAC Inhibitors and Immune Checkpoint Blockade

Oncolytic viruses (OVs) target and destroy cancer cells while sparing their normal counterparts. These viruses have been evaluated in numerous studies at both pre-clinical and clinical levels and the recent Food and Drug Administration (FDA) approval of an oncolytic herpesvirus-based treatment raise...

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Dettagli Bibliografici
Pubblicato in:Viruses
Autori principali: Marchini, Antonio, Scott, Eleanor M., Rommelaere, Jean
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2016
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728569/
https://ncbi.nlm.nih.gov/pubmed/26751469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v8010009
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