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Overcoming Barriers in Oncolytic Virotherapy with HDAC Inhibitors and Immune Checkpoint Blockade

Oncolytic viruses (OVs) target and destroy cancer cells while sparing their normal counterparts. These viruses have been evaluated in numerous studies at both pre-clinical and clinical levels and the recent Food and Drug Administration (FDA) approval of an oncolytic herpesvirus-based treatment raise...

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Detalles Bibliográficos
Publicado en:Viruses
Main Authors: Marchini, Antonio, Scott, Eleanor M., Rommelaere, Jean
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728569/
https://ncbi.nlm.nih.gov/pubmed/26751469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v8010009
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