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Localized oncolytic virotherapy overcomes systemic tumor resistance to immune checkpoint blockade immunotherapy
Preexisting lymphocytic infiltration of tumors is associated with superior prognostic outcomes in a variety of cancers. Recent studies also suggest that lymphocytic responses may identify patients more likely to benefit from therapies targeting immune checkpoints, suggesting that therapeutic efficac...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4106918/ https://ncbi.nlm.nih.gov/pubmed/24598590 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3008095 |
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