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Fine-mapping genetic associations

Whilst thousands of genetic variants have been associated with human traits, identifying the subset of those variants that are causal requires a further ‘fine-mapping’ step. We review the basic fine-mapping approach, which is computationally fast and requires only summary data, but depends on an ass...

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Publicat a:Hum Mol Genet
Autors principals: Hutchinson, Anna, Asimit, Jennifer, Wallace, Chris
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7733401/
https://ncbi.nlm.nih.gov/pubmed/32744321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddaa148
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