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Improving the coverage of credible sets in Bayesian genetic fine-mapping

Genome Wide Association Studies (GWAS) have successfully identified thousands of loci associated with human diseases. Bayesian genetic fine-mapping studies aim to identify the specific causal variants within GWAS loci responsible for each association, reporting credible sets of plausible causal vari...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Hutchinson, Anna, Watson, Hope, Wallace, Chris
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7179948/
https://ncbi.nlm.nih.gov/pubmed/32282791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007829
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