Genetic fine mapping of systemic lupus erythematosus MHC associations in Europeans and African Americans

Genetic variation within the major histocompatibility complex (MHC) contributes substantial risk for systemic lupus erythematosus, but high gene density, extreme polymorphism and extensive linkage disequilibrium (LD) have made fine mapping challenging. To address the problem, we compared two associa...

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Bibliografske podrobnosti
izdano v:Hum Mol Genet
Main Authors: Hanscombe, Ken B, Morris, David L, Noble, Janelle A, Dilthey, Alexander T, Tombleson, Philip, Kaufman, Kenneth M, Comeau, Mary, Langefeld, Carl D, Alarcon-Riquelme, Marta E, Gaffney, Patrick M, Jacob, Chaim O, Sivils, Kathy L, Tsao, Betty P, Alarcon, Graciela S, Brown, Elizabeth E, Croker, Jennifer, Edberg, Jeff, Gilkeson, Gary, James, Judith A, Kamen, Diane L, Kelly, Jennifer A, McCune, Joseph, Merrill, Joan T, Petri, Michelle, Ramsey-Goldman, Rosalind, Reveille, John D, Salmon, Jane E, Scofield, Hal, Utset, Tammy, Wallace, Daniel J, Weisman, Michael H, Kimberly, Robert P, Harley, John B, Lewis, Cathryn M, Criswell, Lindsey A, Vyse, Timothy J
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2018
Teme:
Association Studies Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6196648/
https://ncbi.nlm.nih.gov/pubmed/30085094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddy280
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