RNA-Binding Protein HuR Suppresses Inflammation and Promotes Extracellular Matrix Homeostasis via NKRF in Intervertebral Disc Degeneration

Intervertebral disc degeneration (IVDD) has been reported to be a major cause of low back pain. Studies have demonstrated that IVDD may be dysregulated at the transcriptional level; however, whether post-transcriptional regulation is involved is still unknown. The current study aimed to illustrate t...

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Veröffentlicht in:Front Cell Dev Biol
Hauptverfasser: Shao, Zhenxuan, Tu, Zhuolong, Shi, Yifeng, Li, Sunlong, Wu, Aimin, Wu, Yaosen, Tian, Naifeng, Sun, Liaojun, Pan, Zongyou, Chen, Linwei, Gao, Weiyang, Zhou, Yifei, Wang, Xiangyang, Zhang, Xiaolei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Cell and Developmental Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7732619/
https://ncbi.nlm.nih.gov/pubmed/33330514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.611234
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