High glucose suppresses autophagy through the AMPK pathway while it induces autophagy via oxidative stress in chondrocytes

Diabetes (DB) is a risk factor for osteoarthritis progression. High glucose (HG) is one of the key pathological features of DB and has been demonstrated to induce apoptosis and senescence in chondrocytes. Autophagy is an endogenous mechanism that can protect cells against apoptosis and senescence. T...

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Detaylı Bibliyografya
Yayımlandı:Cell Death Dis
Asıl Yazarlar: Wang, Ben, Shi, Yifeng, Chen, Jiaoxiang, Shao, Zhenxuan, Ni, Libin, Lin, Yan, Wu, Yaosen, Tian, Naifeng, Zhou, Yifei, Sun, Liaojun, Wu, Aimin, Hong, Zhenghua, Wang, Xiangyang, Zhang, Xiaolei
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2021
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8131591/
https://ncbi.nlm.nih.gov/pubmed/34006821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03791-9
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