NAD+ Metabolism Regulates Preadipocyte Differentiation by Enhancing α-Ketoglutarate-Mediated Histone H3K9 Demethylation at the PPARγ Promoter

Obesity has become a serious problem in public health worldwide, causing numerous metabolic diseases. Once the differentiation to mature adipocytes is disrupted, adipocyte hypertrophy and ectopic lipid accumulation leads to the inflammation in adipose tissue and systemic metabolic disorders. Intrace...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Cell Dev Biol
Prif Awduron: Okabe, Keisuke, Nawaz, Allah, Nishida, Yasuhiro, Yaku, Keisuke, Usui, Isao, Tobe, Kazuyuki, Nakagawa, Takashi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2020
Pynciau:
Cell and Developmental Biology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7732485/
https://ncbi.nlm.nih.gov/pubmed/33330464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.586179
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