Sirt1 activator induces proangiogenic genes in preadipocytes to rescue insulin resistance in diet-induced obese mice

Sirt1 plays an important role in regulating glucose and lipid metabolism in obese animal models. Impaired adipose tissue angiogenesis in the obese state decreases adipogenesis and thereby contributes to glucose intolerance and lipid metabolism. However, the mechanism by which Sirt1 activation affect...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Nawaz, Allah, Mehmood, Arshad, Kanatani, Yukiko, Kado, Tomonobu, Igarashi, Yoshiko, Takikawa, Akiko, Yamamoto, Seiji, Okabe, Keisuke, Nakagawa, Takashi, Yagi, Kunimasa, Fujisaka, Shiho, Tobe, Kazuyuki
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6063897/
https://ncbi.nlm.nih.gov/pubmed/30054532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29773-0
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